Table 1.
Sexual dysfunction: Comparison between the groups on buprenorphine-based opioid substitution and control groups
| Sexual dysfunction | OST group (n=40), n (%) | Control group (n=50)#, n (%) | Chi-square/unpaired t-test (P) |
|---|---|---|---|
| As per ASEX, n (%) | 16 (40) | 4 (8) | 13.166 (0.0003) |
| As per IIEF cut off scores, n (%) | |||
| ED (<25) | 31 (77.5) | 8 (16) | 34.229 (<0.0001) |
| Orgasmic dysfunction (<9) | 27 (67.5) | 5 (10) | 32.065 (<0.0001) |
| Sexual desire (<9) | 37 (92.5) | 18 (36) | 29.85 (<0.0001) |
| Intercourse satisfaction (<13) | 38 (95) | 16 (32) | 34.172 (<0.0001) |
| Overall satisfaction (<9) | 33 (82.5) | 18 (36) | 19.568 (<0.0001) |
| As per IIEF scores, mean±SD | |||
| ED | 19.47±5.06 | 26.3±2.8 | 8.11 (<0.0001) |
| Orgasmic dysfunction | 7.35±1.92 | 9.48±0.76 | 7.15 (<0.0001) |
| Sexual desire | 6.17±1.53 | 8.76±1.2 | 9.56 (<0.0001) |
| Intercourse satisfaction | 7.98±2.21 | 13.04±1.48 | 12.9 (<0.0001) |
| Overall satisfaction | 6.05±2.29 | 8.98±1.04 | 8.1 (<0.0001) |
#Data quoted from a published study (Kandappan et al., 2014). OST – Opioid substitution therapy; ASEX – Arizona Sexual Experience Scale Questionnaire; IIEF – International Index of Erectile Function; SD – Standard deviation; ED – Erectile dysfunction