Table 3.

Predictive performance of TNM stage by edition, including sensitivity analyses

	Harrell’s C statistic (95% CI)		Akaike information criterion
	Sixth edition	Seventh edition	Sixth edition	Seventh edition
Entire cohort (n = 2366)
TNM stage broad	0.64 (0.63–0.65)	0.68 (0.67–0.69)	27,112	26,861
TNM stage refined	0.64 (0.63–0.65)	0.68 (0.67–0.69)	27,110	26,843
Excluding unknown stage (n = 2046)
TNM stage broad	0.64 (0.63–0.65)	0.69 (0.68–0.70)	22,539	22,343
TNM stage refined	0.64 (0.63–0.65)	0.69 (0.68–0.71)	22,536	22,324
Excluding GEJ tumours (n = 1761)
TNM stage broad	0.65 (0.64–0.66)	0.69 (0.68–0.70)	18,955	18,777
TNM stage refined	0.65 (0.64–0.66)	0.69 (0.68–0.71)	18,951	18,763
Surgical resection (n = 944)
TNM stage broad	0.66 (0.64–0.68)	0.68 (0.66–0.70)	7793	7761
TNM stage refined	0.66 (0.64–0.69)	0.69 (0.67–0.71)	7789	7746
Non-metastatic (n = 846)
TNM stage broad	0.72 (0.69–0.74)	0.70 (0.68–0.72)	6741	8006
TNM stage refined	0.72 (0.70–0.74)	0.72 (0.70–0.74)	6737	7984

TNM tumour, lymph node, metastasis; n sample size; CI confidence intervals