Fig. 3.

PKD1 modulates glucose metabolism and enhances proliferation, invasion and migration in pancreatic cancer cells. HPAF-II and BxPC3 cells were treated with l-lactate (2 µM) and 2-deoxyglucose (2DG, 10 µM). a, b MTT reagent was added to the cells, and absorbance was recorded following 48 h. c–f Boyden chamber migration and Matrigel invasion assays were performed by staining cells with crystal violet following 18 and 24 h, respectively. The migratory and invasive cells were quantified and are represented by the plotted graphs. All images were captured at ×200. P-values are denoted by *P < 0.05