Figure 4.
Eze inhibited microglia/macrophage activation and neutrophil infiltration at 24 h after MCAO. (a, c) Immunofluorescence revealed that treatment with Eze reduced the number of MPO-positive cells and Iba-1-positive cells in the ischemic penumbra region. (b, d) Representative western blot bands and quantitative analyses of MPO and Iba-1 protein levels at 24 h after MCAO. ∗p < 0.05 vs. sham; #p < 0.05 vs. vehicle. n = 6 per group. Eze: Ezetimibe. Scale bar = 100 μm.
