Figure 5.
Eze reduced oxidative stress injury at 24 h after MCAO. (a) Representative microphotograph of DHE staining in the ischemic penumbra region. (b) Quantitative analysis of DHE-positive cells in the ischemic penumbra region. (c) The MDA level in the ischemic penumbra region. (d) Representative western blot band and quantitative analysis of Romo-1 expression. (e, f) Representative western blot bands and quantitative analyses of total-Nrf2 and nuclear-Nrf2 expression. ∗p < 0.05 vs. sham; #p < 0.05 vs. vehicle. n = 6 per group. DHE: dihydroethidium; Eze: Ezetimibe; MDA: malonaldehyde. Scale bar = 100 μm.
