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Dorsomorphin and Nrf2 siRNA reversed the neuroprotective effects of Eze after MCAO. (a) Representative image of TTC-staining brain slices, (b) quantified infarction volumes, (c) modified Garcia scores, and (d) beam walking scores at 24 h after MCAO. ∗p < 0.05 vs. sham, #p < 0.05 vs. vehicle, &p < 0.05 vs. Eze+DMSO, and @p < 0.05 vs. Eze+Scr siRNA. n = 6 per group. Dorso: dorsomorphin; Eze: Ezetimibe; Scr siRNA: scramble siRNA.
