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Eze attenuated oxidative stress and neuroinflammation via the AMPK/Nrf2/TXNIP pathway after MCAO. (a) Representative western blot bands. (b–h) Quantitative analyses of p-AMPK, Nrf2, HO-1, TXNIP, NLRP3, Cleaved Caspase-1, and IL-1β in the ipsilateral hemisphere at 24 h after MCAO. ∗p < 0.05 vs. sham, #p < 0.05 vs. vehicle, &p < 0.05 vs. Eze+DMSO, and @p < 0.05 vs. Eze+Scr siRNA. n = 6 per group. Eze: Ezetimibe; Scr siRNA: scramble siRNA.
