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. 2020 Jan 15;48(2):e133–e140. doi: 10.1097/CCM.0000000000004095

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Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine and Wolters Kluwer Health, Inc.

This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Postcardiopulmonary resuscitation mitochondrial complex I injury. Oxygen consumption rate (OCR) measurements of cardiac mitochondria from cardiac arrest (CA) and sham. A, The sequential injection of mitochondrial inhibitors is indicated by arrows. B, Adenosine diphosphate (ADP)-stimulated OCR. C, State 3/state 4 respiration. D, Carbonilcyanide p-triflouromethoxyphenylhydrazone-stimulated OCR. E, Calculated proton leak. n = 7, respectively. 12 min CA (CA₁₂) + reperfusion 15 min (R₁₅) = 12-min CA + 15-min resuscitation; *p < 0.05; **p < 0.01; ***p < 0.001 versus sham.