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. 2019 Nov 20;75(1):98–102. doi: 10.1097/FJC.0000000000000764

FIGURE 1.

FIGURE 1.

Effect of IL-15 on left ventricular function and infarct size. A, MI was induced in C57BL/6 mice at day 0. IL-15 (10 μg) or saline as control was administered through IP injection every 6 hours into the animals twice at the day of MI and 3 times on the following days as indicated. B–C, Left ventricular function was evaluated by echocardiography on the day before MI (−1) and at days 1 and 28 after MI. B, IL-15 significantly improved LVEF. C, Stroke volume was significantly higher after IL-15 treatment. D, On average, IL-15 treatment significantly reduced the infarct size by 1.7-fold. E, As indicated by Masson's trichrome staining in the representative figures, IL-15 treatment resulted significantly reduced infarct size compared with the saline-treated control. Inline graphicIL-15, n = 28. Inline graphicsaline, n = 26. *P < 0.05. Error bars are SEM.