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. 2020 Jan 16;15(1):e0227631. doi: 10.1371/journal.pone.0227631

Fig 11. Representative light microphotographs of H & E stained sections from cortex of AD-like model and NAR treated rats at 400x magnification.

Fig 11

(A) Control rat brain showing intact circular neurons with clear nuclei (long arrows). Neurons in AD (B) and AD+DPZ (C) showed cytoplasmic vacuolation (long arrows), damaged, irregular and degenerated neurons (arrow head) and perinuclear space. Rats pre-ted with NAR (D, E) had normal neuronal morphology with less cytoplasmic vacuolation and perinuclear space, intact neurons was observed in NAR+AD (E) (long arrows).