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. 2020 Jan 10;7:356. doi: 10.3389/fcell.2019.00356

FIGURE 2.

FIGURE 2

mTBI exposure and liraglutide/twincretin treatment do not impact the overall condition of the mice, as assessed in the elevated plus maze at both 7 and 30 days post trauma. Anxiety-like behavior assessment at 7 (A) and 30 (B) days post injury. The time spent in open arms of the maze was recorded and compared between groups. One-way ANOVA analysis showed that there were no differences between groups and that all groups of mice spent equivalent times in the open arms at both 7 and 30 days post mTBI [A: F(3,56) = 0.064; NS and B: F(3,51) = 0.374; NS]. Values are mean ± SEM. Locomotor activity at 7 (C) and 30 (D) days post injury. The number of total entrances to the arms of the maze was recorded and compared between groups. One-way ANOVA analysis demonstrated that there were no differences between the groups and all groups of mice had an approximately equal number of entrances to the arms at both 7 and 30 days post mTBI [C: F(3,56) = 0.830; NS, and D: F(3,51) = 0.218; NS]. Values are mean ± SEM.