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Biochemical toxicities in the first three months after radioembolization. A Bilirubin measurements in mg/dl; B–D Alkaline phosphatase, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in U/l. One patients developed a grade 5 REILD with deteriorating bilirubin levels (A) and increasing ALT values at 3 months (D). One patient had isolated AST elevation prior to radioembolization (C) potentially related to prior treatment with everolimus
