Table 4.

Absolute percentages of biochemical and haematological toxicities

CTCAE grade*	Baseline			4–6 weeks			3 months
	0 (%)	1 + 2 (%)	3 + 4 (%)	0 (%)	1 + 2 (%)	3 + 4 (%)	0 (%)	1 + 2 (%)	3 + 4 (%)
ALP	47	51	2	25	75		25	75
γGT	15	47	38	5	41	54	3	31	66
AST	75	23	2	64	36		55	45
ALT	79	21		78	22		76	22	2
Bilirubin	95	5		90	8	3	87	10	3
Albumin	73	27		64	36		55	45
LDH	61	37	2	56	44		69	28	3
Haemoglobin	27	73		29	71		25	75
Leucocytes	75	25		77	23		75	23	2
Lymphocytes	45	32	23	18	54	26	25	33	42
Platelets	82	17	2	69	29	2	70	28	3
INR	100			100			100

CTCAE Common terminology criteria for adverse events version 4.03, ALP alkaline phosphatase, γGT γ-glutamyl transpeptidase, AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase and INR International Normalized Ratio