Table 2.
Characteristic |
<30 y (N = 1248) |
30–34 (N = 1831) |
35–37 (N = 819) |
38–40 (N = 522) |
41–43 (N = 308) |
44–50 (N = 230) |
P |
---|---|---|---|---|---|---|---|
Number of frozen embryos | 2,278 | 3,277 | 1,418 | 885 | 514 | 383 | |
Number of viable embryos after thawed | 2,272 | 3,262 | 1,411 | 879 | 514 | 382 | |
Embryo quality | |||||||
High-quality embryos | 2,262 (99.59%) | 3,240 (99.33%) | 1,403 (99.45%) | 870 (99.02%) | 509 (98.98%) | 375 (98.04%) | a, b, c, d, e* |
Low-quality embryos | 10 (0.41%) | 22 (0.67%) | 8 (0.55%) | 9 (0.98%) | 5 (0.97%) | 7 (1.96%) | |
Number of embryo transferred | |||||||
1 | 342 | 488 | 201 | 143 | 86 | 70 | a, b, c, d, e |
2 | 1,930 | 2,774 | 1,210 | 736 | 428 | 312 | |
Embryo developmental stage at transfer | |||||||
Cleavage stage embryos | 2,085 | 3,015 | 1,291 | 808 | 460 | 365 | a, b, c, d, e* |
Blastocyst stage embryo | 187 | 247 | 120 | 71 | 54 | 17 | |
Clinical pregnancy rate per transfer | 56.09% (700/1,248) | 49.97% (915/1,831) | 47.99% (393/819) | 36.78% (192/522) | 25.00% (77/308) | 12.17% (28/230) | a*, b*, c*, d*, e* |
Implantation rate | 40.63% (923/2,272) | 35.74% (1,166/3,262) | 33.09% (467/1,411) | 25.03% (220/879) | 15.37% (79/514) | 7.59% (29/382) | a*, b*, c*, d*, e* |
Miscarriage rate | 8.43% (59/700) | 11.48% (105/915) | 12.21% (48/393) | 29.69% (57/192) | 36.36% (28/77) | 64.29% (18/28) | a*, b*, c*, d*, e* |
Multiple pregnancy rate | 31.86% (223/700) | 27.43% (251/915) | 18.82% (74/393) | 14.58% (28/192) | 2.59% (2/77) | 3.57% (1/28) | a, b*, c*, d*, e* |
Ectopic pregnancy rate | 4.02% (29/722) | 3.08% (29/942) | 1.51% (6/399) | 3.52% (7/199) | 2.53% (2/79) | 0% (0/28) | a, b, c, d, e* |
Live birth rate | 51.12% (638/1,248) | 43.86% (803/1,831) | 41.64% (341/819) | 25.67% (134/522) | 15.58% (48/308) | 4.78% (11/230) | a*, b*, c*, d*, e* |
a:<30 y vs. 30–34 y.
b: 30–34 vs. 35–37 y.
c: <30 y vs. 35–37 y.
d: 38–40 y vs. 41–43 y.
e: 41–43 y vs. 44–50 y.
P < 0.05.