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. 2020 Jan 10;6:316. doi: 10.3389/fmed.2019.00316

Table 2.

Reproductive outcomes biy age group.

Characteristic <30 y
(N = 1248)
30–34
(N = 1831)
35–37
(N = 819)
38–40
(N = 522)
41–43
(N = 308)
44–50
(N = 230)
P
Number of frozen embryos 2,278 3,277 1,418 885 514 383
Number of viable embryos after thawed 2,272 3,262 1,411 879 514 382
Embryo quality
High-quality embryos 2,262 (99.59%) 3,240 (99.33%) 1,403 (99.45%) 870 (99.02%) 509 (98.98%) 375 (98.04%) a, b, c, d, e*
Low-quality embryos 10 (0.41%) 22 (0.67%) 8 (0.55%) 9 (0.98%) 5 (0.97%) 7 (1.96%)
Number of embryo transferred
    1 342 488 201 143 86 70 a, b, c, d, e
    2 1,930 2,774 1,210 736 428 312
Embryo developmental stage at transfer
    Cleavage stage embryos 2,085 3,015 1,291 808 460 365 a, b, c, d, e*
    Blastocyst stage embryo 187 247 120 71 54 17
    Clinical pregnancy rate per transfer 56.09% (700/1,248) 49.97% (915/1,831) 47.99% (393/819) 36.78% (192/522) 25.00% (77/308) 12.17% (28/230) a*, b*, c*, d*, e*
    Implantation rate 40.63% (923/2,272) 35.74% (1,166/3,262) 33.09% (467/1,411) 25.03% (220/879) 15.37% (79/514) 7.59% (29/382) a*, b*, c*, d*, e*
    Miscarriage rate 8.43% (59/700) 11.48% (105/915) 12.21% (48/393) 29.69% (57/192) 36.36% (28/77) 64.29% (18/28) a*, b*, c*, d*, e*
    Multiple pregnancy rate 31.86% (223/700) 27.43% (251/915) 18.82% (74/393) 14.58% (28/192) 2.59% (2/77) 3.57% (1/28) a, b*, c*, d*, e*
    Ectopic pregnancy rate 4.02% (29/722) 3.08% (29/942) 1.51% (6/399) 3.52% (7/199) 2.53% (2/79) 0% (0/28) a, b, c, d, e*
    Live birth rate 51.12% (638/1,248) 43.86% (803/1,831) 41.64% (341/819) 25.67% (134/522) 15.58% (48/308) 4.78% (11/230) a*, b*, c*, d*, e*

a:<30 y vs. 30–34 y.

b: 30–34 vs. 35–37 y.

c: <30 y vs. 35–37 y.

d: 38–40 y vs. 41–43 y.

e: 41–43 y vs. 44–50 y.

*:

P < 0.05.