Table 4.
Crude and AORs for pregnancy and adverse neonatal outcomes in singleton births.
| Characteristics | <30 y | 30–34 y | 35–37 | 38–40 | 41–43 | 44–50 |
|---|---|---|---|---|---|---|
| Clinical pregnancy | ||||||
| Crude OR(95% CI) | Reference | 0.80 (0.69–0.92) | 0.74 (0.62–0.88) | 0.47 (0.38–0.58) | 0.27 (0.20–0.35) | 0.11 (0.08–0.17) |
| aOR(95% CI) | Reference | 0.84 (0.73–0.97) | 0.82 (0.68–0.99) | 0.52 (0.42–0.65) | 0.30 (0.22–0.40) | 0.13 (0.09–0.20) |
| Miscarriage | ||||||
| Crude OR(95% CI) | Reference | 1.50 (1.07–2.12) | 1.58 (1.05–2.38) | 4.78 (3.15–7.24) | 6.63 (3.86–11.37) | 20.88 (9.19–47.44) |
| aOR(95% CI) | Reference | 1.49 (1.06–2.11) | 1.55 (1.01–2.29) | 4.29 (2.78–6.62) | 5.92 (3.38–10.39) | 17.99 (7.77–41.66) |
| Ectopic pregnancy | ||||||
| Crude OR(95% CI) | Reference | 1.00 (0.57–1.75) | 0.56 (0.24–1.33) | 1.15 (0.48–2.73) | 0.82 (0.19–3.55) | NA |
| aOR(95% CI) | Reference | 1.01 (0.57–1.80) | 0.57 (0.24–1.38) | 1.18 (0.48–2.91) | 0.70 (0.16–3.15) | NA |
| Live birth | ||||||
| Crude OR(95% CI) | Reference | 0.75 (0.65–0.86) | 0.68 (0.57–0.82) | 0.33 (0.26–0.41) | 0.18 (0.13–0.25) | 0.04 (0.02–0.08) |
| aOR(95% CI) | Reference | 0.78 (0.67–0.90) | 0.76 (0.63–0.91) | 0.37 (0.30–0.47) | 0.20 (0.14–0.28) | 0.05 (0.03–0.10) |
| VLBW (<1,500 g) | ||||||
| Crude OR(95% CI) | Reference | 1.05 (0.80–1.38) | 0.85 (0.61–1.17) | 0.80 (0.52–1.23) | 1.48 (0.73–3.00) | NA |
| aOR(95% CI) | Reference | 1.01 (0.77–1.33) | 0.75 (0.54–1.05) | 0.64 (0.41–1.01) | 1.20 (0.58–2.47) | NA |
| LBW (<2,500 g) | ||||||
| Crude OR(95% CI) | Reference | 0.95 (0.53–1.71) | 1.23 (0.63–2.40) | 1.06 (0.42–2.70) | 0.42 (0.06–3.22) | NA |
| aOR(95% CI) | Reference | 1.00 (0.56–1.81) | 1.26 (0.63–2.51) | 1.15 (0.44–3.02) | 0.47 (0.06–3.66) | NA |
| Macrosomia(>4,000 g) | ||||||
| Crude OR(95% CI) | Reference | 1.34 (0.80–2.22) | 0.75 (0.37–1.53) | 1.04 (0.44–2.47) | 0.72 (0.17–3.14) | NA |
| aOR(95% CI) | Reference | 1.35 (0.81–2.26) | 0.70 (0.34–1.45) | 0.87 (0.35–2.14) | 0.68 (0.15–3.05) | NA |
| Very PTD (<32 weeks) | ||||||
| Crude OR(95% CI) | Reference | 1.24 (0.45–3.45) | 0.53 (0.11–2.63) | 0.78 (0.45–1.38) | 1.03 (0.73–1.43) | NA |
| aOR(95% CI) | Reference | 1.27 (0.47–3.48) | 0.51 (0.09–2.61) | 0.75 (0.45–1.29) | 1.05 (0.74–1.47) | NA |
| PTD (<37 weeks) | ||||||
| Crude OR(95% CI) | Reference | 1.10 (0.68–1.78) | 1.18 (0.67–2.10) | 0.86 (0.37–2.00) | 0.29 (0.04–2.18) | NA |
| aOR(95% CI) | Reference | 1.12 (0.69–1.81) | 1.16 (0.65–2.09) | 0.85 (0.36–2.04) | 0.28 (0.04–2.10) | NA |
Analyses were adjusted for maternal body mass index, gravidity, parity, duration of infertility (continuous), infertility diagnosis, fertilization method, previous FET attempts, fertilization method, FET endometrial preparation, embryo developmental stage at transfer and number of embryos transferred. CI, confidence interval; OR, odds ratio; aOR, adjusted odds ratios. NA, not available.