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. 2020 Jan 16;5:2. doi: 10.1038/s41525-019-0108-5

Fig. 1. Mesenchymal and proneural GSCs have distinct alternative splicing profiles, but a similar number of genes harboring alternative splicing events.

Fig. 1

a Hierarchical cluster showing that GSCs can be grouped based on their alternative splicing profile (PSI values). Bootstrap (bp) and approximately unbiased (AU) probability from pvclust.89 b Percentage of events and number of genes harboring exon skipping (ES), mutually exclusive exons (MXE), alternative 3′ or 3′ splice site (ASS), and retained introns (RI) events in MES or PN GSCs. c Quantitative RT-PCR (qRT-PCR) validation of four exon-skipping events in PN and MES GSCs. ELMOD3, FDFT1, OSBPL6, and RAB18 are official gene names. d An exon- skipping event (gene OSBPL6; second exon) in PN and MES GSCs. e qRT-PCR validation of three exon-skipping events in MES and PN GSCs. GSN, SLC9A5, and WASF3 are official gene names. d An exon-skipping event (gene GSN; second exon) in MES and PN GSCs.