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. 2020 Jan 16;11:333. doi: 10.1038/s41467-019-14085-2

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Fig. 2 — a KDELR3 (red) and GFP (green) staining in E17.5 iDct-GFP mouse skin. White arrows depict co-localization. Magnification, ×40. Scale bars, 20 µm. Representative image of 100 cells analyzed taken from one mouse. b Pan-cancer RNA expression of KDEL receptors in human cell lines (NCI60, CellMiner analysis); KDELR3 expression in melanoma (black line). c KDELR3 expression in human nevus and melanoma lymph node metastasis (red intercellular staining), magnification, ×10. Scale bar represents 200 µm. d H score of KDELR3 immunohistochemistry in human tumor microarrays. Unpaired two-tailed Student’s t test with Welch’s correction, P = 0.0003, d.f. = 47.9, t = 3.936. N = 21 (nevus) and N = 75 (melanoma). e KDELR3 expression in benign nevi and malignant melanoma (GSE3189; 204017_at probeset). Unpaired two-tailed Student’s t test with Welch’s correction, P < 0.0001, d.f. = 47.39, t = 6.035. N = 18 (benign nevi) and N = 45 (malignant melanoma). d, e Line and error bars represent mean ± s.e.m.