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. 2020 Jan 10;10:3040. doi: 10.3389/fimmu.2019.03040

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Copyright © 2020 Lin, Fulzele, Cohen, Bennett and Wasserman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The bombardier gene is specifically required for Toll-mediated defense. (A–D) Survival curves of flies infected as indicated. The w¹¹¹⁸ strain was the wild-type control; Bom^Δ55C and Rel^E20 were the susceptible controls (24, 40). Experiments were completed in triplicate with at least 25 flies per genotype in each replicate. Statistical significance was determined using the Gehan-Breslow-Wilcoxon test and Δbbd is shown relative to w¹¹¹⁸ in black, relative to Bom^Δ55C in orange, and relative to Rel^E20 in red (^***p < 0.0001; n.s., not significant, p > 0.05).