Table 4.
Combinations of polymorphisms
| SNP1 | SNP2 | Case, N (%) | Control, N (%) | Adjusted OR, 95% CI* | P (OR) |
|---|---|---|---|---|---|
| NFKB1 -94ins/del ATTG | NFKBIA 3’UTR A>G | ||||
| II | AA | 97 (5.51) | 106 (5.81) | Referent | |
| II | AG | 230 (13.08) | 232 (12.71) | 1.134 (0.812, 1.584) | 0.460 |
| II | GG | 172 (9.78) | 155 (8.49) | 1.254 (0.880, 1.788) | 0.211 |
| ID | AA | 174 (9.89) | 182 (9.97) | 1.086 (0.766, 1.540) | 0.641 |
| ID | AG | 409 (23.25) | 447 (24.48) | 1.028 (0.754, 1.401) | 0.861 |
| ID | GG | 289 (16.43) | 295 (16.16) | 1.101 (0.797, 1.521) | 0.559 |
| DD | AA | 77 (4.38) | 77 (4.22) | 1.109 (0.726, 1.694) | 0.632 |
| DD | AG | 193 (10.97) | 198 (10.84) | 1.081 (0.767, 1.523) | 0.657 |
| DD | GG | 118 (6.71) | 134 (7.34) | 0.994 (0.683, 1.445) | 0.973 |
| NFKBIA 3’UTR A>G | DAZL A386G (T54A) | ||||
| AA | AA | 323 (18.36) | 322 (17.63) | Referent | |
| AA | AG | 25 (1.42) | 43 (2.35) | 0.617 (0.366, 1.041) | 0.071 |
| AA | GG | 0 (0.00) | 0 (0.00) | - | - |
| AG | AA | 762 (43.32) | 785 (42.99) | 0.980 (0.814, 1.180) | 0.832 |
| AG | AG | 70 (3.98) | 91 (4.98) | 0.778 (0.548, 1.106) | 0.162 |
| AG | GG | 0 (0.00) | 1 (0.05) | - | - |
| GG | AA | 522 (29.68) | 527 (28.86) | 0.996 (0.817, 1.215) | 0.971 |
| GG | AG | 57 (3.24) | 56 (3.07) | 1.073 (0.716, 1.607) | 0.732 |
| GG | GG | 0 (0.00) | 1 (0.05) | - | - |
| NFKB1 -94ins/del ATTG | DAZL A386G (T54A) | ||||
| II | AA | 457 (25.98) | 455 (24.92) | Referent | |
| II | AG | 42 (2.39) | 47 (2.57) | 0.877 (0.564, 1.363) | 0.559 |
| II | GG | 0 (0.00) | 1 (0.05) | - | - |
| ID | AA | 796 (45.25) | 838 (45.89) | 0.921 (0.781, 1.085) | 0.326 |
| ID | AG | 76 (4.32) | 85 (4.65) | 0.896 (0.638, 1.258) | 0.526 |
| ID | GG | 0 (0.00) | 1 (0.05) | - | - |
| DD | AA | 354 (20.13) | 351 (19.22) | 0.966 (0.792, 1.179) | 0.735 |
| DD | AG | 34 (1.93) | 58 (3.18) | 0.588 (0.376, 0.919) | 0.020 |
| DD | GG | 0 (0.00) | 0 (0.00) | - | - |
*
Adjusted for age, BMI, smoking status and alcohol drinking habit.