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Effects of ATG4A on osteosarcoma cell proliferation. (A) The mRNA and protein level of ATG4A after knockdown and overexpression in SAOS2 and HOS cell lines. Knockdown of ATG4A inhibited SAOS2 cell proliferation (B) and clone formation ability (D). Overexpression of ATG4A promotes HOS cell proliferation (C) and clone formation ability (E). *P<0.05. NC, negative control.
