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. 2017 Jul 1;10(7):7270–7276.

Table 1.

Correlation between IHC and FISH in HER-2 status

IHC Score FISH Status Total Concordance

Negative Equivocal Positive
-/+ 148 1 9 158 93.67% (148/158)
++ 198 12 100 310 32.26% (100/310)
+++ 42 5 74 121 61.16% (74/121)
Total 388 18 183 589

IHC, immunohistochemistry; FISH, fluorescence in situ hybridization. Kappa = 0.189, P = 0.000; r = 0.427, P = 0.000.