TABLE 1.
Sl no. | Plasmid | Speciesa | Accession no. | CRISPR-array position | DR-length (bp) | No. of spacers | Plasmid size (kb) | Replicon typeb | Antibiotic resistance genes identified (annotation by ResFinderc) |
1 | pKPM501 | Kp | CP031735.1 | 200609–201185 | 28 | 9 | 253 | IncFIBk, IncFIIk | blaCTX–M–15, blaTEM–1A, aac(6′)-Ib, aac(6′)-Ib-cr, dfrA14 |
2 | unnamed_1 | Kp | CP022612.1 | 313185–313943 | 29 | 12 | 335 | IncHI1, IncHI1B, IncFIB, IncR | blaNDM–1, blaCTX–M–15, blaTEM–1A, blaOXA–9, blaSHV–13, aph(3′)-VI, armA, aadA2, aadA1, aac(6′)-Ib, aac(6′)-Ib-cr, aac(3)-IId, aph(6)-Id, sul1,2,3; dfrA12 |
3 | AR_0153 plasmid unnamed1 | Kp | CP028929.1 | 62241–63001 | 29 | 12 | 283 | IncHI1B, IncFIB | blaNDM–1, blaOXA–1, aph(3′)-VI, armA, aadA2, aac(6′)-Ib-cr, qnrB1, sul1, dfrA12, dfrA14 |
4 | pKPN528-1 | Kp | CP020854.1 | 251737–252495 | 29 | 12 | 292 | IncHI1B, IncFIB | blaNDM–1, blaOXA–1, aph(3′)-VI, armA, aadA2, aac(6′)-Ib-cr, qnrB1, sul1, dfrA12, dfrA14 |
5 | AR_0068 plasmid unitig_1 | Kp | CP020068.1 | 136244–137004 | 29 | 12 | 276 | IncHI1B, IncFIB | blaNDM–1, blaSHV–13, aph(3′)-VI, armA, aadA2, aac(3)-IId, aph(6)-Id, sul1,2; dfrA12 |
6 | pIncHI1B_DHQP1300920 | Kp | CP016921.1 | 229597–230357 | 29 | 12 | 283 | IncHI1B, IncFIB | blaNDM–1, blaOXA–1, aph(3′)-VI, armA, aadA2, aac(6′)-Ib-cr, qnrB1, sul1, dfrA12, dfrA14 |
7 | KP617 plasmid KP-plasmid1 | Kp | CP012754.1 | 114404–115164 | 29 | 12 | 273 | IncHI1B, IncFIB | blaNDM–1, aph(3′)-VI, armA, aadA2, qnrB1, sul1, dfrA12 |
8 | PittNDM01 plasmid1 | Kp | CP006799.1 | 114132–114892 | 29 | 12 | 283 | IncHI1B, IncFIB | blaNDM–1, blaOXA–1, aph(3′)-VI, armA, aadA2, aac(6′)-Ib-cr, qnrB1, sul1, dfrA12, dfrA14 |
9 | pKJNM10C3.2 | Kp | CP030878.1 | 136256–137016 | 29 | 12 | 276 | IncHI1B, IncFIB | blaNDM–7, aph(3′)-VI, armA, aadA2, aph(3′′)-Ib, aph(6)-Id, aac(3)-IIa, sul1, 2; dfrA12 |
10 | p18ES-342 | Kp | CM008881 | 52979–53610 | 23 | 10 | 332 | IncHI1B, IncFIB | dfrA1 |
11 | unnamed1 | Kp | CP031818 | 223392–224022 | 23 | 10 | 430 | IncFIB | None |
12 | pKpvST147L | Kp | CM007852 | 167552–168555 | 29 | 16 | 343 | IncHI1B, IncFIB | armA, aph(3′)-Ia, sul1, 2; dfrA5 |
13 | KSB2_1B plasmid unnamed1 | Kp | CP024507.1 | 41987–42747 | 29 | 12 | 310 | IncFIB | None |
14 | pKp_Goe_414-1 | Kp | CP018339.1 | 75291–76111 | 29 | 13 | 204 | IncFIB | None |
15 | pKPN-3967 | Kp | CP026186.1 | 221215–221302 | 27 | 1 | 373 | IncFIB | None |
16 | p44-1 | Kp | CP025462.1 | 42604–43120 | 29 | 8 | 261 | IncFIB | None |
17 | TVGHCRE225 plasmid unnamed1 | Kp | CP023723.1 | 10881–11763 | 29 | 14 | 297 | IncHI1B, IncFIB | None |
18 | pOXA1_020030 | Kp | CP028791.1 | 30205–30843 | 29 | 10 | 288 | IncFIB | blaOXA–1, aac(6′)-Ib-cr, sul1 |
19 | 825795-1 plasmid unnamed1 | Kp | CP017986.1 | 148524–149585 | 30 | 17 | 244 | IncHI1B, IncFIB | None |
20 | pKp_Goe_304-1 | Kp | CP018720.1 | 24563–25679 | 24 | 18 | 246 | IncHI1B, IncFIB | None |
21 | pKp_Goe_021-1 | Kp | CP018714.1 | 7697–8748 | 30 | 17 | 246 | IncHI1B, IncFIB | None |
22 | pKp_Goe_026-1 | Kp | CP018708.1 | 54661–55777 | 24 | 18 | 246 | IncHI1B, IncFIB | None |
23 | pKp_Goe_024-1 | Kp | CP018702.1 | 5006–6122 | 24 | 18 | 246 | IncHI1B, IncFIB | None |
24 | pKp_Goe_832-1 | Kp | CP018696.1 | 102143–103259 | 24 | 18 | 246 | IncHI1B, IncFIB | None |
25 | pKp_Goe_473-1 | Kp | CP018687.1 | 116666–117727 | 30 | 17 | 246 | IncHI1B, IncFIB | None |
26 | pKp_Goe_579-1 | Kp | CP018313.1 | 94773–95834 | 30 | 17 | 246 | IncHI1B, IncFIB | None |
27 | AR_0363 plasmid unnamed4 | Kp | CP027156.1 | 127062–128305 | 29 | 20 | 186 | IncHI1B, IncFIB | aac(6′)-Ib, aac(6′)-Ib-cr |
28 | pKPN-edaa | Kp | CP026398.1 | 7401–8525 | 29 | 18 | 249 | IncHI1B, IncFIB | blaNDM–1, blaOXA–1, blaDHA–1, aph(3′′)-Ib, aph(6)-Id, aac(6′)-Ib-cr, qnrB4, sul1 |
29 | pKPN-bbef | Kp | CP026172.1 | 227283–228407 | 29 | 18 | 244 | IncHI1B, IncFIB | None |
30 | pKpvST101_5 | Kp | CP031372.1 | 144828–145262 | 25 | 10 | 210 | IncHI1B, IncFIB | None |
31 | pKpn23412-362 | Kp | CP011314.1 | 141865–142618 | 23 | 12 | 362 | IncHI1B, IncFIB | blaOXA–1, blaCTX–M–15, blaTEM–1B, blaOXA–1, aac(3)-IIa, aph(3′′)-Ib, aph(6)-Id, aac(6′)-Ib-cr, sul2, dfr1 |
32 | p1502320-3 | Kp | CP031580.1 | 7608–8781 | 29 | 19 | 87 | ND | None |
33 | pKP3301 DNA | Kp | AP018748.1 | 3677–4373 | 29 | 11 | 296 | IncHI1B, IncFIB | blaNDM–1, blaCTX–M–15, blaTEM–1A, blaOXA–1, aph(3′)-VI, armA, aadA2, aac(6′)-Ib, aac(6′)-Ib-cr |
34 | SKGH01 plasmid unnamed 1 | Kp | CP015501.1 | 7545–7875 | 29 | 15 | 281 | IncHI1B, IncFIB | None |
35 | Plasmid_A_Kpneumoniae_MS6671 | Kp | LN824134.1 | 16764–17823 | 29 | 17 | 280 | IncHI1B, IncFIB | None |
36 | pKJNM8C2.1 | Kp | CP030858.1 | 10639–11155 | 30 | 8 | 304 | IncHI1B, IncFIB | blaNDM–1, blaCTX–M–15, blaOXA–1, armA, aadA2, aac(6′)-Ib-cr, qnrB1, sul1, dfrA12 |
37 | pPMK1-NDM | Kp | CP008933.1 | 10628–11144 | 30 | 8 | 304 | IncHI1B, IncFIB | blaNDM–1, blaCTX–M–15, blaOXA–1, armA, aadA2, aac(6′)-Ib-cr, qnrB1, sul1, dfrA12 |
38 | pFB2.1 | Pg | CP014776.1 | 56849–57852 | 29 | 16 | 242 | IncFIB | None |
39 | pE20-HI3 | Kp | MG288682.1 | 27978–29043 | 29 | 17 | 240 | IncFIB | blaOXA–1, armA, aac(6′)-Ib-cr, sul1 |
40 | pEC422_1 | Ec | CP018961.1 | 276922–277868 | 29 | 15 | 290 | IncHI1B, IncFIB | blaCTX–M–2, blaTEM–1B, blaOXA–1, aac(6′)-Ib-cr, aac(3)-IIa, sul1 |
41 | pNDM-TJ03 | Kp | MG845201.1 | 130378–131435 | 29 | 17 | 280 | IncHI1B, IncFIB | blaNDM–1, blaOXA–1, blaSHV–12, blaDHA–1, aph(3′′)-Ib, aph(6)-Id, aac(6′)-Ib-cr, qnrB4, sul1 |
42 | pNDM-TJ11 | Ko | MG845200.1 | 130294–131351 | 29 | 17 | 275 | IncHI1B, IncFIB | blaNDM–1, blaOXA–1, blaDHA–1, aph(3′′)-Ib, aph(6)-Id, aac(6′)-Ib-cr, qnrB4, sul1 |
43 | pENVA | Kp | HG918041.1 | 99454–100629 | 23 | 19 | 254 | IncHI1B, IncFIB | blaNDM–1, blaOXA–1, blaSHV–12, blaDHA–1, aph(3′′)-Ib, aph(6)-Id, aac(6′)-Ib-cr, qnrB4, sul1 |
44 | pKP64477b | Kp | MF150122.1 | 84064–85428 | 29 | 22 | 205 | IncHI1B, IncFIB | None |
45 | Raoultella ornithinolytica strain 18 plasmid 1 | Ro | CP012556.1 | 115417–115897 | 29 | 7 | 216 | ND | None |
46 | pKPN1481-1 | Kv | CP020848.1 | 325794–326308 | 29 | 8 | 347 | IncHI1B, IncFIB | blaNDM–1, blaCTX–M–15, blaOXA–1, blaTEM–1A, blaOXA–9, aac(6′)-Ib, aac(6′)-Ib-cr, aadA1, qnrB1 |
47 | pK66-45-1 | Kp | CP020902.1 | None | 0 | 0 | 338 | IncFIB, IncFII, IncHI1B, IncR | blaNDM–1, blaCTX–M–15, armA, aadA2, aph(3′)-VI, qnrS1, sul1, dfrA12 |
aKp, K. pneumoniae; Pg, Pluralibacter gergoviae; Ec, E. coli; Ko, Klebsiella oxytoca; Ro, Raoultella ornithinolytica; Kv, Klebsiella variicola.bND, not detected.caac(6′)-Ib also commonly annotated as aacA4; aph(3′′)-Ib, aph(6)-Id also commonly annotated as strA, strB.