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. 2020 Jan 10;10:1536. doi: 10.3389/fphar.2019.01536

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Copyright © 2020 Zhu, Lu, Jiang, Yao, Jiang, Huang, Jiang, Peng, Fu and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hypoxia. (A) Dihydroethidium (DHE) staining was performed on the islets after 24 h cultivation for all groups. (B) Representatives of HIF-1α immunohistochemical staining of the islet graft in each group. a: FREE group; b: 60 ng bFGF group; c: 1 mg RHC group; d: 16 mg RHC group; e: 1 mg–60 ng RHC-bFGF group; f: 16 mg–60 ng RHC-bFGF group.