Figure 3.

MiR-641 inhibited EMT process in A549 cells. A549 cells were transfected with miR-641 mimic, miR-641 inhibitor and their corresponding controls. After inducing by 10 ng/ml of TGF-β1, A. The mRNAs and B. The protein levels of E-cadherin, N-cadherin, Vimentin, ZEB1 and Snail were detected by RT-qPCR and western blot. MiR-641: microRNA-641; EMT: epithelial mesenchymal transition; TGF-β1: transforming growth factor-beta 1; ZEB1: Zinc finger E-box-binding homeobox 1; RT-qPCR: real-time quantitative PCR; *, P < 0.05.