Figure 4.

Gene Correction Frequency

Gene correction frequency values were calculated as the ratio between the number of surviving colonies and the total number of cells initially plated. Also shown is a representative image of the number of S23 repaired colonies obtained after the treatment with HpS23E1rep repair-PPRH in cells transfected either in asynchronous conditions or in S phase. After selection, surviving cell colonies were fixed with formaldehyde and stained with crystal violet. Error bars represent the standard error of the mean of three experiments. *p < 0.05.