Table 2.
Therapeutic effect of taurine and ascorbic acid on MDA, GSH, SOD, catalase and Gpx in spinal cord injury-induced male albino rats
| Oxidative markers | Group I (Sham) | Group II (control) | Group III (100 mg/kg of taurine) | Group IV (100 mg/kg of ascorbic acid) | Group V (100 mg/kg of taurine + 100 mg/kg of ascorbic acid) |
|---|---|---|---|---|---|
| GSH (mg/g) | 81.4 ± 3.15 | 30.2 ± 1.2### | 45.2 ± 2.2* | 48.4 ± 2.5* | 75.9 ± 3.8*** |
| SOD (U/mg) | 8.2 ± 0.2 | 3.3 ± 0.1### | 4.9 ± 0.2* | 5.2 ± 0.2* | 7.8 ± 0.3*** |
| Catalase (U/g) | 14.2 ± 1 | 4.1 ± 0.1### | 7.8 ± 0.2* | 8.6 ± 0.3* | 12.7 ± 0.7*** |
| Gpx (mg/protein) | 0.98 ± 0.001 | 0.31 ± 0.005## | 0.52 ± 0.003* | 0.67 ± 0.005* | 0.84 ± 0.01*** |
| MDA (nmol/g) | 20.5 ± 1.1 | 77 ± 3### | 51.6 ± 2* | 49.5 ± 2.5* | 28.4 ± 1.2*** |
##P < 0.01, ###P < 0.001, *P < 0.05, ***P < 0.001