Fig. 9.

Transmission electron microscopy images of cross-sections of a regenerated peripheral nerve. (A) 2 weeks after OCT implantation, the nuclei of Schwann cells surround by unmyelinated axons are observed (arrow). (B) 4 weeks after OCT implantation, myelinated axons are observed (arrowhead). (C) Images of intact tissue. (D) The thickness of the myelin sheath as measured using Image-J soft. Ten myelin sheaths are selected from the central region of the regenerated peripheral nerve. The thickness in the OCT group is significantly lower than that in the intact group (P < 0.01).