Table 1.

The electrometric response to aldosterone

	V t (mV)			R t (Ω·cm2)			I eq (μA·cm−2)
	Baseline	3‐hr treatment	Amil.	Baseline	3‐hr treatment	Amil.	Baseline	3‐hr treatment	Amil.
Vehicle	−17.2 ± 5.9	−16.3 ± 5.1	0.5 ± 0.7#	2105 ± 342	2125 ± 363	3340 ± 650#	−7.8 ± 1.6	−7.4 ± 1.4	0.1 ± 0.2#
Aldo.	−18.1 ± 5.2	−36.7 ± 7.4*	−5.9 ± 3.2* , #	2277 ± 257	1666 ± 113*	3261 ± 461#	−7.7 ± 1.5	−5.9 ± 3.2*	−1.6 ± 0.8* , #

Note. Electrometric measurements (V _t and R _t) were recorded, allowing calculation of equivalent short circuit current (I _eq), from cells grown on filters under control (vehicle) or aldosterone‐treated conditions. Measurements were made before treatment (baseline); 3 hr after treatment (3‐hr treatment) with solvent vehicle or aldosterone (Aldo, 3 nM); and 5 min after exposure to amiloride (Amil., 10 μM). Data are mean ± 95% confidence interval (n = 12). Statistical significance was determined using a repeated‐measures two‐way ANOVA. Where appropriate, multiple comparisons were determined by Tukey's post hoc test.

^* P<0.05, significantly different from vehicle‐treated cells.

^# P<0.05, significant difference between 3‐hr treatment and amiloride.