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Schematic diagram of the antifibrotic effect of praziquantel in inhibition of hepatic stellate cells activation. Praziquantel increased the expression of Smad7 that inhibited Smad2/3 phosphorylation to inhibit the TGF‐β/Smad signalling. This can further result in the inhibition of HSCs activation and extracellular matrix (ECM) production
