Table 3.
Risk of incident hip fracture with respect to metabolic factors in quintiles; HR, hazard ratio.
| Exposures in quintiles | Quintile level (1, lowest; 5, highest) | Men |
Women |
||||||
|---|---|---|---|---|---|---|---|---|---|
| HR (95% CI)a | ptrend | HR (95% CI)b | ptrend | HR (95% CI)a | ptrend | HR (95% CI)b | ptrend | ||
| BMI | 1 | Reference | Reference | Reference | Reference | ||||
| 2 | 0.61 (0.42,0.87) | 0.0006 | 0.61 (0.43,0.88) | 0.0006 | 1.08 (0.81,1.44) | 0.0159 | 1.09 (0.81,1.45) | 0.0111 | |
| 3 | 0.62 (0.44,0.88) | 0.62 (0.44,0.88) | 0.95 (0.72,1.26) | 0.96 (0.73,1.27) | |||||
| 4 | 0.51 (0.35,0.73) | 0.51 (0.35,0.73) | 0.81 (0.61,1.07) | 0.82 (0.62,1.08) | |||||
| 5 | 0.55 (0.38,0.79) | 0.55 (0.38,0.79) | 0.82 (0.62,1.08) | 0.83 (0.63,1.10) | |||||
| Blood glucose | 1 | Reference | Reference | Reference | Reference | ||||
| 2 | 0.87 (0.59,1.29) | 0.8811 | 0.90 (0.61,1.34) | 0.5612 | 0.94 (0.72,1.22) | 0.1702 | 0.94 (0.72,1.23) | 0.3426 | |
| 3 | 0.99 (0.67,1.45) | 1.05 (0.72,1.54) | 0.93 (0.72,1.20) | 0.94 (0.73,1.22) | |||||
| 4 | 0.73 (0.50,1.08) | 0.79 (0.54,1.18) | 0.73 (0.57,0.95) | 0.76 (0.58,0.98) | |||||
| 5 | 1.01 (0.72,1.43) | 1.15 (0.81,1.64) | 0.90 (0.72,1.12) | 0.94 (0.75,1.17) | |||||
| Cholesterol | 1 | Reference | Reference | Reference | Reference | ||||
| 2 | 0.79 (0.54,1.16) | 0.9667 | 0.82 (0.56,1.21) | 0.7472 | 0.72 (0.52,0.99) | 0.0498 | 0.72 (0.52,0.99) | 0.0459 | |
| 3 | 0.59 (0.39,0.89) | 0.62 (0.41,0.94) | 0.57 (0.42,0.78) | 0.57 (0.42,0.78) | |||||
| 4 | 0.84 (0.58,1.22) | 0.89 (0.61,1.29) | 0.74 (0.56,0.98) | 0.74 (0.56,0.98) | |||||
| 5 | 0.91 (0.63,1.30) | 0.97 (0.68,1.40) | 0.64 (0.49,0.85) | 0.64 (0.48,0.84) | |||||
| Triglycerides | 1 | Reference | Reference | Reference | Reference | ||||
| 2 | 0.91 (0.63,1.32) | 0.6235 | 0.96 (0.66,1.39) | 0.1258 | 1.01 (0.74,1.39) | 0.1243 | 1.02 (0.74,1.40) | 0.2540 | |
| 3 | 0.73 (0.50,1.07) | 0.83 (0.56,1.22) | 0.82 (0.60,1.12) | 0.83 (0.61,1.14) | |||||
| 4 | 1.01 (0.70,1.45) | 1.18 (0.81,1.71) | 0.83 (0.61,1.12) | 0.85 (0.63,1.16) | |||||
| 5 | 1.06 (0.73,1.54) | 1.28 (0.87,1.90) | 0.85 (0.63,1.14) | 0.88 (0.65,1.19) | |||||
| MAP | 1 | Reference | Reference | Reference | Reference | ||||
| 2 | 0.81 (0.52,1.26) | 0.4956 | 0.88 (0.56,1.38) | 0.7837 | 0.90 (0.60,1.36) | 0.1431 | 0.92 (0.61,1.40) | 0.3600 | |
| 3 | 0.83 (0.56,1.24) | 0.93 (0.62,1.39) | 0.79 (0.54,1.16) | 0.82 (0.56,1.20) | |||||
| 4 | 0.81 (0.55,1.20) | 0.95 (0.63,1.41) | 0.72 (0.50,1.04) | 0.77 (0.53,1.10) | |||||
| 5 | 0.84 (0.57,1.23) | 1.01 (0.68,1.49) | 0.78 (0.54,1.11) | 0.84 (0.58,1.20) | |||||
BMI, body mass index; MAP, mean arterial pressure.
a
Cox regression models are stratified by categories of birth year.
b
Cox regression models are stratified by categories of birth year, additionally adjusted for smoking and BMI (except for BMI).