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Effects of DHQ on apoptosis of hepatic cells. DHQ down-regulated the expression of apoptosis proteins in acute injury liver cells. DHQ executed hepatoprotection through inhibited apoptosis. DHQ could result in down-regulation of Bax and up-regulation of Pro-caspase-3 and Bcl-2 based on western blot (A) (n=6). Similarly, DHQ could obviously reduce liver cell apoptosis of mice induced by APAP based on TUNEL staining (B) (n=6).
