Table 2.
Pathological characteristics of IgA nephropathy patients with normal/elevated serum IgA
| Variable | Normal IgA group n=59 | Elevated IgA group n=16 | P-value |
|---|---|---|---|
| Lee’s grade [n (%)] | 0.493 | ||
| Grade II | 5 (8.5) | 0 | |
| Grade III | 26 (44.1) | 7 (43.8) | |
| Grade IV | 4 (35.6) | 8 (50.0) | |
| Grade V | 7 (11.9) | 1 (6.3) | |
| Oxford classification | |||
| M1 [n (%)] | 47 (81.0) | 8 (50.0) | 0.028 |
| E1 [n (%)] | 17 (29.3) | 3 (18.8) | 0.600 |
| S1 [n (%)] | 23 (39.7) | 4 (25.0) | 0.281 |
| Oxford T [n (%)] | 0.366 | ||
| T1 | 28 (48.3) | 7 (43.8) | |
| T2 | 2 (3.4) | 12 (12.5) | |
| Oxford C [n (%)] | 0.415 | ||
| C1 | 37 (63.8) | 13 (81.3) | |
| C2 | 8 (13.8) | 1 (6.3) | |
| IgG (+) | 0 (0, 0) | 0 (0, 0) | 0.055 |
| IgA (+) | 3 (2, 3) | 3 (2, 3) | 0.670 |
| IgM (+) | 1 (1, 1) | 1 (1, 1) | 0.388 |
Abbreviations: Oxford M1, Mesangial score >0.5; Oxford E1, Endo capillary hypercellularity present; Oxford S1, Segmental glomerulosclerosis present; Oxford T, Tubular atrophy/interstitial fbrosis; T1, Tubular atrophy/interstitial fbrosis 26-50%; T2, Tubular atrophy/interstitial fbrosis >50%; Oxford C1, proportion of crescent <25%, Oxford C2, proportion of crescent >25%.