Table 1.
Association between serum miR-138 levels and clinical features in 113 HNSCC patients
| Clinical parameters | Cases (N=113) | MiR-138 levels | P value | |
|---|---|---|---|---|
|
| ||||
| High (n=57) | Low (n=56) | |||
| Age | 0.7838 | |||
| ≤61 | 62 | 32 | 30 | |
| >61 | 51 | 25 | 26 | |
| Gender | 0.5201 | |||
| Men | 101 | 52 | 49 | |
| Women | 12 | 5 | 7 | |
| Tobacco consumption | 0.2667 | |||
| Yes | 40 | 23 | 17 | |
| No | 73 | 34 | 39 | |
| Alcohol consumption | 0.1420 | |||
| Yes | 44 | 26 | 18 | |
| No | 69 | 31 | 38 | |
| Primary tumor sites | 0.2983 | |||
| Oral cavity/oropharynx | 59 | 27 | 32 | |
| Others | 54 | 30 | 24 | |
| pT stage | 0.1091 | |||
| T0-2 | 55 | 32 | 23 | |
| T3-4 | 58 | 25 | 33 | |
| Differentiation | 0.0467* | |||
| Well | 34 | 22 | 12 | |
| Moderate/poor | 79 | 35 | 44 | |
| pN stage | 0.0994 | |||
| N0-1 | 30 | 19 | 11 | |
| N2-3 | 83 | 38 | 45 | |
| Clinical stage | 0.0046* | |||
| I/II | 43 | 29 | 14 | |
| III/IV | 70 | 28 | 42 | |
*
P<0.05 was considered to be statistically significant.