Table 4.
Top 10 significant KEGG pathways of 2,247 co-expressed genes of HOXA13
| Term | Count | P Value | Genes |
|---|---|---|---|
| Calcium signaling pathway | 41 | 1.01E-05 | ADCY1, GNA11, CAMK2G, DRD5, OXTR, BDKRB2, ITPKA, ATP2B1, PRKACG, ATP2B2 etc. |
| cAMP signaling pathway | 43 | 2.36E-05 | PPARA, ATP1B1, ADCY1, ATP1B3, GNAI1, CAMK2G, DRD5, ADCY6, OXTR, GRIN3B etc. |
| Proteoglycans in cancer | 42 | 6.73E-05 | WNT5B, LUM, PPP1R12B, CAMK2G, PPP1R12C, TLR4, PDCD4, ITGB1, HOXD10, PRKACG etc. |
| Peroxisome | 23 | 7.31E-05 | ACOX2, NUDT19, EHHADH, AMACR, CRAT, PEX11G, PEX11A, PEX11B, FAR2, MLYCD etc. |
| Glutamatergic synapse | 28 | 9.83E-05 | SLC38A3, ADCY1, GNAI1, ADCY6, GNG13, GRIK5, GRIN3B, GNG12, KCNJ3, PRKACG etc. |
| Axon guidance | 30 | 1.11E-04 | NRP1, GNAI1, EFNA2, EFNA3, L1CAM, EPHB3, EPHB4, ITGB1, SEMA5A, SEMA7A etc. |
| Cholinergic synapse | 27 | 1.60E-04 | ADCY1, GNAI1, CAMK2G, GNA11, ADCY6, GNG13, GNG12, KCNJ3, PRKACG, KCNQ4 etc. |
| Endocrine and other factor-regulated calcium reabsorption | 15 | 2.46E-04 | PRKCA, ATP1B1, CLTB, ATP1B3, KLK2, ADCY6, PRKCG, BDKRB2, KLK1, PRKACG, VDR etc. |
| Insulin secretion | 22 | 3.09E-04 | PRKCA, TRPM4, ATP1B1, ADCY1, ATP1B3, CAMK2G, GNA11, ADCY6, FFAR1, PRKCG etc. |
| Pancreatic secretion | 23 | 4.33E-04 | PRKCA, ATP1B1, PNLIPRP1, ADCY1, ATP1B3, SLC12A2, ADCY6, PRKCG, ITPR3, ATP2B1 etc. |