Table 5.
Top 10 significant KEGG pathways annotations of 506 higher qualified co-expressing genes of HOXA13
| Term | Count | P Value | Genes |
|---|---|---|---|
| Metabolic pathways | 156 | 5.41E-15 | ALAD, SGMS2, NT5C3A, EHHADH, PTGS1, PPCS, PI4K2B, ACSS2, NMRK1, ITPKA etc. |
| Calcium signaling pathway | 41 | 3.01E-11 | ADCY1, GNA11, CAMK2G, DRD5, OXTR, BDKRB2, ITPKA, ATP2B1, PRKACG, ATP2B2 etc. |
| cAMP signaling pathway | 43 | 5.63E-11 | PPARA, ATP1B1, ADCY1, ATP1B3, GNAI1, CAMK2G, DRD5, ADCY6, OXTR, GRIN3B etc. |
| Pathways in cancer | 64 | 2.92E-10 | FGF6, ADCY1, PPARD, GNA11, ADCY6, PPARG, LPAR1, PTEN, PRKACG, PLCB3 etc. |
| Proteoglycans in cancer | 42 | 2.95E-10 | WNT5B, LUM, PPP1R12B, CAMK2G, PPP1R12C, TLR4, PDCD4, ITGB1, HOXD10, PRKACG etc. |
| Endocytosis | 46 | 9.05E-09 | CLTB, CHMP3, TSG101, CHMP4B, CAPZA2, STAM2, KIAA0196, ASAP2, PIP5K1B, ASAP1 etc. |
| Axon guidance | 30 | 1.02E-08 | NRP1, GNAI1, EFNA2, EFNA3, L1CAM, EPHB3, ITGB1, EPHB4, SEMA5A, SEMA7A etc. |
| Glutamatergic synapse | 28 | 1.45E-08 | SLC38A3, ADCY1, GNAI1, ADCY6, GNG13, GRIK5, GRIN3B, GNG12, KCNJ3, PRKACG etc. |
| Focal adhesion | 39 | 2.93E-08 | TLN2, PPP1R12B, PPP1R12C, ARHGAP35, MYL10, PTEN, ITGB1, LAMB3, ARHGAP5, ITGB8 etc. |
| Neuroactive ligand-receptor interaction | 47 | 2.98E-08 | TSPO, THRA, THRB, DRD5, GRIK5, OXTR, GRIN3B, BDKRB2, LPAR1, VIPR1 etc. |