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F13A inhibits the expression of cytoskeleton and tight junction proteins in human RPE cells under high glucose condition. The expression of cytoskeleton, VE-Cadherin (A) and tight junction, occluding (B) in human RPE cells by laser scanning confocal detection. Staining intensities of apelin in RPE cells were decreased significantly, compared with control ones (B). *P < 0.05, #P < 0.01 versus untreated control.
