Table 2.
Allele frequencies in cases and controls and odds ratio estimates for PTB risk
| SNP | Gene (s) | Locus | Alleles A/B | MAF | HWE p value | OR | 95% CI | p-value | |
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Case | Control | ||||||||
| rs13501 | TAP2 | 6p21.32 | A/G | 0.265 | 0.258 | 0.652 | 1.039 | 0.803-1.345 | 0.768 |
| rs241447 | TAP2 | 6p21.32 | A/G | 0.258 | 0.255 | 0.543 | 1.018 | 0.785-1.319 | 0.895 |
| rs183585 | TAP2 | 6p21.32 | C/T | 0.265 | 0.265 | 0.768 | 1.002 | 0.774-1.296 | 0.99 |
| rs3819721 | TAP2 | 6p21.32 | A/G | 0.233 | 0.192 | 1 | 1.284 | 0.972-1.684 | 0.078 |
| rs1010324 | SEC14L2 | 22q12.2 | A/G | 0.283 | 0.257 | 0.881 | 1.145 | 0.887-1.478 | 0.298 |
| rs1061660 | SEC14L2 | 22q12.2 | C/T | 0.475 | 0.407 | 0.122 | 1.32 | 1.05-1.659 | 0.017* |
SNP: single-nucleotide polymorphism; MAF: minor allele frequency; HWE: Hardy-Weinberg equilibrium; OR: odds ratio; CI: confidence interval.
*
P < 0.05 indicates statistical significance.