Table 2.
Univariate and multivariate analysis of factors associated with overall survival in breast cancer patients
| Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|
|
|
|||||
| Variable | n | RR (95% CI) | P | RR (95% CI) | P |
| Age (year) | |||||
| ≤45 | 35 | 1 | |||
| >45 | 86 | 1.416 (0.643-3.119) | 0.387 | n.a. | n.a. |
| Histological grade | |||||
| I | 30 | 1 | |||
| II-III | 91 | 2.033 (0.789-5.241) | 0.142 | n.a. | n.a. |
| Positive lymph node | |||||
| ≤3 | 83 | 1 | 1 | ||
| >3 | 38 | 2.159 (1.110-4.200) | 0.023 | 1.702 (0.213-13.588) | 0.616 |
| Lymphovascular invasion | |||||
| Absence | 73 | 1 | 1 | ||
| Presence | 48 | 3.588 (1.784-7.216) | <0.001 | 2.708 (1.290-5.681) | 0.008 |
| Tumor size (cm) | |||||
| ≤2 | 30 | 1 | |||
| >2 | 91 | 2.338 (0.907-6.031) | 0.079 | n.a. | n.a. |
| ER | |||||
| Positive | 83 | 1 | 1 | ||
| Negative | 38 | 1.955 (1.005-3.804) | 0.048 | 1.690 (0.855-3.340) | 0.131 |
| PR | |||||
| Positive | 57 | 1 | |||
| Negative | 64 | 1.159 (0.593-2.264) | 0.666 | n.a. | n.a. |
| Her2 | |||||
| Negative | 67 | 1 | 1 | ||
| Positive | 54 | 2.279 (1.158-4.485) | 0.017 | 2.196 (1.111-4.341) | 0.024 |
| TNM stage | |||||
| I-II | 79 | 1 | 1 | ||
| III | 42 | 2.123 (1.094-4.122) | 0.026 | 0.326 (0.039-2.742) | 0.302 |
| GLO1 expression | |||||
| Low | 51 | 1 | 1 | ||
| High | 70 | 4.193 (1.739-10.113) | 0.001 | 2.716 (1.063-6.939) | 0.037 |
Abbreviations: n.a.: Not application; ER, estrogen receptor; PR, progesterone receptor; Her2, Human Epidermal Growth Factor Receptor type 2; TNM, tumor node metastasis.