Table 3.
Univariate and multivariate analysis of factors associated with recurrence-free survival in breast cancer patients
| Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|
|
|
|||||
| Variable | n | RR (95% CI) | P | RR (95% CI) | P |
| Age (year) | |||||
| ≤45 | 35 | 1 | |||
| >45 | 86 | 1.033 (0.542-1.968) | 0.922 | n.a. | n.a. |
| Histological grade | |||||
| I | 30 | 1 | |||
| II-III | 91 | 1.905 (0.851-4.266) | 0.117 | n.a. | n.a. |
| Positive lymph node | |||||
| ≤3 | 83 | 1 | 1 | ||
| >3 | 38 | 2.282 (1.270-4.102) | 0.006 | 1.682 (0.222-12.775) | 0.615 |
| Lymphovascular invasion | |||||
| Absence | 73 | 1 | 1 | ||
| Presence | 48 | 3.192 (1.746-5.837) | <0.001 | 2.356 (1.245-4.456) | 0.008 |
| Tumor size (cm) | |||||
| ≤2 | 30 | 1 | |||
| >2 | 91 | 1.385 (0.686-2.799) | 0.364 | n.a. | n.a. |
| ER | |||||
| Positive | 83 | 1 | |||
| Negative | 38 | 1.568 (0.863-2.848) | 0.140 | n.a. | n.a. |
| PR | |||||
| Positive | 57 | 1 | |||
| Negative | 64 | 1.099 (0.610-1.978) | 0.754 | n.a. | n.a. |
| Her2 | |||||
| Negative | 67 | 1 | 1 | ||
| Positive | 54 | 1.942 (1.078-3.499) | 0.027 | 1.881 (1.042-3.399) | 0.036 |
| TNM stage | |||||
| I-II | 79 | 1 | 1 | ||
| III | 42 | 2.192 (1.221-3.936) | 0.009 | 0.395 (0.049-3.166) | 0.382 |
| GLO1 expression | |||||
| Low | 51 | 1 | 1 | ||
| High | 70 | 4.151 (1.931-8.923) | <0.001 | 2.917 (1.296-6.563) | 0.010 |
Abbreviations: n.a.: Not application; ER, estrogen receptor; PR, progesterone receptor; Her2, Human Epidermal Growth Factor Receptor type 2; TNM, tumor node metastasis.