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EZH2 medicates MiR-26a-regulated tumor cell proliferation and apoptosis. The RT-PCR and WB assays were involved and detected that transfected EZH2 plasmids induced EZH2 regulation by miR-26a in mRNA level and protein expression (A, B). Results from kit-8 assays and colony formation assays showed that mimics-miR26a markedly suppress cell proliferation and colony formation, which was recovered by overexpression of EZH2 (C-F).
