MPO, MDA and SOD in different groups. A: In Ven group, the MPO activity increased markedly as compared to control group (P<0.01), but the celastrol pretreatment significantly inhibited MPO activity (P=0.003<0.01). B: In Ven group, the MDA content increased markedly as compared to control group (P<0.01), but the celastrol pretreatment significantly inhibited increased MDA content (P=0.007<0.01). C: In Ven group, the SOD activity reduced markedly as compared to Con group, but it significantly increased in the presence of celastrol pretreatment (P=0.035<0.05) (*P<0.05 and **P<0.01).