Table 2.
Cytokine concentrations in cancerous tissues and para-cancerous tissues of PTC patients with or without Hashimoto thyroiditis and differences between cancerous tissues and para-cancerous tissues
| Cytokine | PTC with HT | PTC without HT | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| Cancerous Tissue (n=12) x ± SD | Para-cancerous Tissue (n=13) x ± SD | Value of P | Cancerous Tissue (n=6) x ± SD | Para-cancerous Tissue (n=9) x ± SD | Value of P | |
| ICAM-1 | 228184.8 ± 62529.1 | 76012.5 ± 22340.5 | 0.001 | 211812.7 ± 89759.9 | 75850.7 ± 32882.2 | 0.012 |
| IFN-γ | 1.9 ± 0.8 | 3.9 ± 2.0 | 0.004 | 2.3 ± 0.7 | 2.2 ± 1.4 | 0.974 |
| IFN-α | 1.4 ± 0.4 | 1.8 ± 0.5 | 0.048 | 1.5 ± 0.3 | 1.6 ± 0.6 | 0.770 |
| IL-1α | 21.7 ± 11.7 | 18.2 ± 9.4 | 0.415 | 19.0 ± 13.6 | 10.9 ± 6.1 | 0.136 |
| IL-1β | 18.6 ± 19.1 | 25.2 ± 7.4 | 0.261 | 10.9 ± 10.5 | 2.1 ± 1.7 | 0.094 |
| IL-12p70 | 5.6 ± 1.4 | 6.8 ± 3.2 | 0.218 | 5.8 ± 2.1 | 4.2 ± 1.9 | 0.144 |
| IL-8 | 289.2 ± 173.2 | 190.1 ± 68.0 | 0.085 | 191.1 ± 105.1 | 104.7 ± 41.2 | 0.103 |
| IP-10 | 414.4 ± 272.7 | 518.0 ± 168.9 | 0.261 | 317.9 ± 193.1 | 265.6 ± 65.5 | 0.548 |
| MCP-1 | 2257.6 ± 1024.2 | 3097.7 ± 1244.2 | 0.080 | 2308.5 ± 810.0 | 2109.4 ± 653.0 | 0.607 |
| MIP-1α | 97.5 ± 26.8 | 83.7 ± 19.8 | 0.153 | 148.8 ± 171.6 | 47.5 ± 18.9 | 0.208 |
| MIP-1β | 628.9 ± 702.3 | 432.2 ± 164.8 | 0.362 | 384.6 ± 235.3 | 223.8 ± 118.7 | 0.168 |
| sE-Selectin | 6783.0 ± 2984.7 | 7792.5 ± 2219.0 | 0.345 | 6763.0 ± 2831.6 | 4100.1 ± 1677.3 | 0.038 |