Table 2.

Multivariate survival analysis of overall survival in 120 osteosarcoma patients

Variables	Hazard ratio	95% CI	P
Age	0.58	0.42-1.17	0.286
Gender	1.29	0.93-2.77	0.573
Tumor location	0.87	0.64-1.54	0.742
Tumor size	1.23	0.89-2.67	0.193
Clinical stage	2.84	2.16-7.45	0.026
Tumor grade	1.47	1.03-2.48	0.12
Distant Metastasis	4.72	3.86-10.15	0.017
Response to chemotherapy	0.93	0.67-2.34	0.163
miR-34a level	3.18	2.87-9.56	0.001