Table 3.
Top 50 down-regulated genes in primary aldosteronism
| Rank | Gene name | Fold change | P value |
|---|---|---|---|
| 1 | HAS2 | 0.0507 | 0.0014 |
| 2 | HOXD10 | 0.0560 | 0.0449 |
| 3 | DDX50P1 | 0.0573 | 0.0332 |
| 4 | GALNT5 | 0.0587 | 0.0063 |
| 5 | PTPRT | 0.0627 | 0.0044 |
| 6 | IGFL4 | 0.0707 | 0.0000 |
| 7 | IGFN1 | 0.0731 | 0.0010 |
| 8 | RIMKLBP2 | 0.0923 | 0.0024 |
| 9 | RP11-219B17.1 | 0.0925 | 0.0087 |
| 10 | HEXA-AS1 | 0.0932 | 0.0396 |
| 11 | DHRS9 | 0.0942 | 0.0374 |
| 12 | PTPN20CP | 0.1011 | 0.0457 |
| 13 | AC018766.6 | 0.1025 | 0.0445 |
| 14 | COL11A1 | 0.1067 | 0.0001 |
| 15 | RP5-1184F4.5 | 0.1084 | 0.0158 |
| 16 | CLRN1-AS1 | 0.1088 | 0.0278 |
| 17 | QRFPR | 0.1138 | 0.0026 |
| 18 | RP11-701H24.3 | 0.1195 | 0.0253 |
| 19 | RP11-164N3.3 | 0.1210 | 0.0293 |
| 20 | ANGPT2 | 0.1225 | 0.0007 |
| 21 | SP5 | 0.1235 | 0.0059 |
| 22 | HS6ST3 | 0.1258 | 0.0130 |
| 23 | CLIC6 | 0.1306 | 0.0230 |
| 24 | RP11-171A24.3 | 0.1366 | 0.0280 |
| 25 | CABP7 | 0.1374 | 0.0039 |
| 26 | SEMA3D | 0.1397 | 0.0005 |
| 27 | PRSS35 | 0.1405 | 0.0009 |
| 28 | RP11-673E1.1 | 0.1410 | 0.0483 |
| 29 | HOXA11 | 0.1420 | 0.0135 |
| 30 | LMAN1L | 0.1445 | 0.0483 |
| 31 | RP11-134K13.2 | 0.1475 | 0.0121 |
| 32 | AP000688.29 | 0.1557 | 0.0007 |
| 33 | SPACA6P-AS | 0.1559 | 0.0328 |
| 34 | NDNF | 0.1562 | 0.0003 |
| 35 | RP11-276H19.1 | 0.1625 | 0.0128 |
| 36 | CDKL5 | 0.1636 | 0.0357 |
| 37 | ENPP6 | 0.1769 | 0.0253 |
| 38 | HIST2H2BA | 0.1847 | 0.0106 |
| 39 | PCDHB12 | 0.1908 | 0.0157 |
| 40 | MAL2 | 0.1925 | 0.0058 |
| 41 | RP1-78O14.1 | 0.1933 | 0.0163 |
| 42 | SLC9A2 | 0.1933 | 0.0020 |
| 43 | RP11-384P7.7 | 0.1998 | 0.0327 |
| 44 | RP3-468K18.6 | 0.2013 | 0.0351 |
| 45 | AP001468.1 | 0.2048 | 0.0449 |
| 46 | RP11-61A14.2 | 0.2052 | 0.0279 |
| 47 | KCNA4 | 0.2056 | 0.0001 |
| 48 | RELN | 0.2066 | 0.0165 |
| 49 | ATP2B2 | 0.2134 | 0.0028 |
| 50 | DDIT4L | 0.2269 | 0.0059 |