Figure 3.

Emodin affected cell proliferation and invasion via down regulating Notch1 in two bladder cancer cell lines. A and B: Expression of Notch1 was inhibited by emodin in both NC cells and over-expressed cells (n=3). C and D: Cell proliferation was inhibited in emodin medication groups (n=3). E: Cell invasion was significantly depressed in emodin medication groups (n=3). Data were shown as mean ± S.D., *P<0.05, **P<0.01 (compared with negative controls); #P<0.05, ##P<0.01 (compared with Notch1 groups).