Table 6.
Association of SNPs and HTGW stratified analysis by sex
| Sex | SNPs | Genotypes | OR (95% CI) | P value |
|---|---|---|---|---|
| Male | rs780094 | GG | 1 | - |
| AG | 0.410 (0.423-1.192) | 0.195 | ||
| AA | 0.838 (0.541-1.297) | 0.428 | ||
| AA vs. AG+GG | 0.911 (0.558-1.486) | 0.709 | ||
| AA+AG vs. GG | 1.333 (0.827-2.150) | 0.238 | ||
| rs10830963 | CC | 1 | - | |
| GC | 0.903 (0.568-1.435) | 0.666 | ||
| GG | 1.908 (0.611-1.971) | 0.755 | ||
| GG vs. GC+CC | 1.162 (0.686-1.966) | 0.577 | ||
| GG+GC vs. CC | 0.957 (0.622-1.472) | 0.841 | ||
| rs151290 | AA | 1 | - | |
| CA | 1.083 (0.556-2.110) | 0.814 | ||
| CC | 0.777 (0.390-1.550) | 0.474 | ||
| CC vs. CA+AA | 0.728 (0.474-1.119) | 0.148 | ||
| CC+CA vs. AA | 1.556 (0.996-2.433) | 0.052 | ||
| rs972283 | GG | 1 | - | |
| GA | 0.964 (0.621-1.495) | 0.869 | ||
| AA | 1.164 (0.551-2.459) | 0.691 | ||
| AA vs. GA+GG | 1.182 (0.572-2.442) | 0.651 | ||
| AA+GA vs. GG | 0.999 (0.660-1.510) | 0.995 | ||
| Female | rs780094 | GG | 1 | - |
| AG | 0.545 (0.296-1.003) | 0.051 | ||
| AA | 1.343 (0.699-2.578) | 0.376 | ||
| AA vs. AG+GG | 0.884 (0.531-1.474) | 0.638 | ||
| AA+AG vs. GG | 1.640 (0.938-2.867) | 0.083 | ||
| rs10830963 | CC | 1 | - | |
| GC | 0.827 (0.492-1.390) | 0.474 | ||
| GG | 1.093 (0.563-2.123) | 0.793 | ||
| GG vs. GC+CC | 1.211 (0.664-2.208) | 0.531 | ||
| GG+GC vs. CC | 0.898 (0.554-1.455) | 0.661 | ||
| rs151290 | AA | 1 | - | |
| CA | 1.382 (0.653-2.923) | 0.397 | ||
| CC | 0.711 (0.330-1.532) | 0.383 | ||
| CC vs. CA+AA | 0.550 (0.337-0.900) | 0.017 | ||
| CC+CA vs. AA | 1.730 (1.053-2.843) | 0.031 | ||
| rs972283 | GG | 1 | - | |
| GA | 1.027 (0.627-1.682) | 0.915 | ||
| AA | 0.755 (0.331-1.723) | 0.505 | ||
| AA vs. GA+GG | 0.746 (0.337-1.654) | 0.471 | ||
| AA+GA vs. GG | 0.968 (0.608-1.542) | 0.891 |
Adjusted for age, FPG, SBP, DBP, and behavior risk factors.