Figure 1.

The capture efficiency and linearity of the current methodology. A: Model CTC samples were prepared by spiking different amounts of SK-OV-3 cells into 7.5 mL of healthy donors’ blood; the samples were then processed by the IsoFlux System. The average recovery percentage across all spike-in levels was 70.2 (±13.3)%. Standard errors of 4 parallel samples are shown for each spiked concentration. B: The R² value was 0.97 with a slope of 0.77 (77% of cells captured).