Table 2.
Relationship between MAD2L1 expression and clinical pathological factor of BRCA
| Parameters | MAD2L1 staining | χ2 | P value | |
|---|---|---|---|---|
|
| ||||
| Negative (%) | Positive (+-+++) (%) | |||
| Age (years) | 2.171 | 0.141 | ||
| ≤50 | 51 (46.4) | 59 (53.6) | ||
| >50 | 56 (56.6) | 43 (43.4) | ||
| Histological grade | 4.852 | 0.028 | ||
| I+II | 66 (57.9) | 48 (42.1) | ||
| III | 40 (42.6) | 54 (57.4) | ||
| Tumor size (cm) | 0.857 | 0.652 | ||
| ≤2 | 32 (56.1) | 25 (43.9) | ||
| 2-5 | 64 (48.9) | 67 (51.1) | ||
| >5 | 11 (52.4) | 10 (47.6) | ||
| Lymph node metastasis (N) | 1.936 | 0.164 | ||
| No (N0) | 58 (56.3) | 45 (43.7) | ||
| Yes (N1-N3) | 49 (46.7) | 56 (53.3) | ||
| Distant metastasis (M) | 0.159 | 1.000 | ||
| M0 | 104 (51.0) | 100 (49.0) | ||
| M1 | 3 (60.0) | 2 (40.0) | ||
| Clinical stage | 2.047 | 0.152 | ||
| I+II | 79 (54.5) | 66 (45.5) | ||
| III+IV | 28 (43.8) | 36 (56.3) | ||
Note: χ2 test was conducted to examine MAD2L1 expression in groups of different clinicopathological parameters of BRCA.