Table 3.
Relationship between MAD2L1 expression and ER, PR, P53, HER-2, Ki-67
| Variables | MAD2L1 staining | χ2 | P value | |
|---|---|---|---|---|
|
| ||||
| Negative (-) (%) | Positive (+-+++) (%) | |||
| ER | 5.786 | 0.016 | ||
| Negative | 33 (40.7) | 48 (59.3) | ||
| Positive | 74 (57.8) | 54 (42.2) | ||
| PR | 2.691 | 0.101 | ||
| Negative | 44 (45.4) | 53 (54.6) | ||
| Positive | 63 (56.8) | 48 (43.2) | ||
| P53 | 5.745 | 0.017 | ||
| Negative | 70 (58.3) | 50 (41.7) | ||
| Positive | 37 (41.6) | 52 (58.4) | ||
| HER-2 | 16.647 | <0.001 | ||
| Negative | 86 (61.0) | 55 (39.0) | ||
| Positive | 21 (30.9) | 47 (69.1) | ||
| Ki-67 | 11.531 | 0.001 | ||
| Negative | 65 (63.1) | 38 (36.9) | ||
| Positive | 42 (39.6) | 64 (60.4) | ||
Note: ER: estrogen receptor; PR: progesterone receptor; HER-2: human epidermal growth factor receptor 2; χ2 test was conducted to assess the relationship between MAD2L1 expression and ER, PR, P53, HER-2, Ki-67.