Table 2.
Comparison of the genotype and allele frequencies of the CYP26A1 rs2068888 SNP in the Maonan and Han populations [n (%)]
| Group | n | Genotype | Allele | P HWE | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| AA | AG | GG | A | G | |||
| Mannan | 833 | 629 (75.51) | 195 (23.41) | 9 (1.08) | 1453 (87.22) | 213 (12.78) | 0.331 |
| Han | 701 | 453 (64.62) | 232 (33.10) | 16 (2.28) | 1138 (81.17) | 264 (18.83) | 0.342 |
| χ2 | 22.603 | 21.189 | |||||
| P | 0.000 | 0.000 | |||||
| Mannan | |||||||
| Male | 335 | 251 (74.93) | 81 (24.18) | 3 (0.90) | 583 (87.01) | 87 (12.99) | 0.329 |
| Female | 498 | 378 (75.90) | 114 (22.89) | 6 (1.20) | 870 (87.35) | 126 (12.65) | 0.334 |
| χ2 | 0.345 | 0.040 | |||||
| P | 0.837 | 0.841 | |||||
| Han | |||||||
| Male | 270 | 175 (64.81) | 88 (32.59) | 7 (2.59) | 438 (81.11) | 102 (18.89) | 0.346 |
| Female | 431 | 278 (64.50) | 144 (33.41) | 9 (2.09) | 700 (81.21) | 162 (18.79) | 0.340 |
| χ2 | 0.221 | 0.002 | |||||
| P | 0.895 | 0.965 | |||||
HWE, the Hardy-Weinberg equilibrium. The genotype distribution between the two groups was analyzed by the chi-square test. The Hardy-Weinberg equilibrium was analyzed by the chi-square test of the goodness of fit.